Streamlining RNA-LNP & nanoparticle manufacturing
Once your RNA and lipids are ready, TAMARA enables the reproducible formulation of RNA-LNPs from early screening to preclinical studies. Built for formulation R&D, it combines:
1 µg to 5 mg of encapsulated RNA per run
A reusable microfluidic chip with two mixer designs on one reversible chip
Zero formulation losses, >90% RNA recovery
What can TAMARA do?
Whether you're screening lipid formulations or exploring different payload options, TAMARA adapts to your needs.
can formulate
A few of our core formulation capabilities
- Lipid nanoparticles (RNA-LNP…)
- Liposomes, micelles, polyplexes
- Polymer & hybrid nanoparticles
- Peptide nanoparticles
can encapsulate
Most common cargos you can load
- mRNA, saRNA, circRNA
- siRNA, miRNA
- CRISPR-Cas9
- ASOs & DNA
- Small molecules & peptides
you can address
Wide range of therapeutic areas
- Preventive and therapeutic vaccines
- Gene editing & rare disease
- Oncology
- Personalized medicine
Your LNP stays the same as you scale up
With TAMARA, a single instrument carries your formulation across the entire R&D workflow. Because the chip, the mixer and the process stay identical from a 0.2 mL screen to a 30 mL preclinical batch, your nanoparticle keeps the same size, PDI and encapsulation efficiency at every scale — so your in vivo readouts reflect the biology, not a change of instrument.
The technology behind the speed
Microfluidic mixing is the reference method for RNA-LNP formulation. It allows for:
- Best size control and reproducibility through flow condition control (TFR & FRR)
- High encapsulation efficiency (EE >95%)
- Excellent in vitro & in vivo performance
- Accurate formulation from µL to mL volumes
Fastest mixing for the smallest LNPs. Gold standard in RNA-LNP formulation.
Robust secondary-flow design for broader flexibility.
Two minutes to understand TAMARA
An intuitive 3-step process, even for a first-time user. It's that simple.
Choose your mixer and set the flow conditions for your target LNP.
Load your RNA and lipid phases directly — no priming, no dead volume.
Start the run and recover your RNA-LNPs, reproducibly, in minutes.
Make the most of every microgram
Once your RNA is ready, every microgram counts. TAMARA's chip design avoids the dead-volume losses common to single-use systems, recovering more than 90% of your input RNA.
Reusable chips, cleaned between runs with a built-in protocol, also remove the recurring cost of disposable cartridges.
It's only through daily use that the true value of a machine becomes apparent. When PhD students consistently gravitate toward one device while overlooking others, it speaks volumes. TAMARA is in high demand — an endorsement in itself.
Editor, IJP & JCR
See TAMARA run, live
Book a demo with our team — online or at your lab — and see a full RNA-LNP formulation run from set-up to result.