01
More than a formulation reagent
Ncapsulate® encompasses proprietary delivery chemistries, optimized formulation processes, off-the-shelf formulation products, and formulation-development expertise designed specifically for RNA medicines.
Why choose our CNP?
02
QCX at the core
QCX is a proprietary class of lipid-like delivery molecules developed to achieve efficient RNA encapsulation, cellular delivery, endosomal escape and RNA release - while reducing dependence on heavily patented ionizable-lipid families. Structurally distinct from incumbent ionizable lipids such as ALC-0315 (Pfizer/BioNTech) and SM-102 (Moderna), the lead compound QCX-002 pairs an ionizable amine (pKa ~6.5) and a biodegradable ester with independently functionalizable head (R2) and tail (R1) groups - a tunable platform backed by two Quantoom-owned patent families, freedom-to-operate by design.
03
Built to remove real limitations
It addresses the key constraints of current LNP development: complex IP landscapes, difficult access to formulation know-how, specialized equipment requirements, reproducibility challenges and stringent storage conditions.
04
Coherent with the rest of N-Force
By integrating formulation science with upstream RNA design and downstream production, Ncapsulate® enables a coherent pathway from RNA sequence to formulated RNA product.
CNP architecture
Same nanoparticle. One decisive swap.
A conventional lipid nanoparticle (LNP) carries RNA with four lipid roles: a PEG-lipid, cholesterol, a helper lipid, and a complexing lipid (i-lipid). That last piece is what packs the RNA and helps it escape into the cell — and it is also where most of the patented chemistry sits.
Quantoom keeps the same particle. The only change is the complexing lipid: instead of a standard i-lipid, we use our CNP — a lipid-like calixarene chemistry, with QCX-002 as the lead molecule. Same three supporting lipids, same RNA cargo, a different engine at the centre.
Off-the-shelf QCX products
Core and Combo kits for flexible workflows and faster process development.
Ncapsulate QCX core
- QCX molecule as a raw material
- Integrates into any formulation workflow
- Ready for formulation customization
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