mRNA Formulation
mRNA Delivery for mRNA-based vaccines
COMING SOON
The importance of Lipid Nanoparticles
mRNA formulation in lipid nanoparticles (LNPs) is paramount for vaccine and therapeutic effectiveness. Proper formulation enhances mRNA stability, protects it from degradation and extends shelf-life, while ensuring efficient cellular uptake.
Current solutions
don’t suffice
Current conventional workflows rely heavily on repurposed equipment, which is typically used for other applications such as biologics and immunotherapy bioprocessing. This equipment is not always ideally suited to the specific needs of these applications, particularly for drug-product purification, which often employs methods that are poorly scalable, induce high shear stress, and can result in significant product losses. Additionally, managing multiple pieces of equipment can be complex. These systems often require significant floorspace and dedicated rooms, as well as extensive documentation, SOPs, and thorough training of personnel.
Our innovative solution integrates mRNA-LNP mixing and downstream purification in a single piece of equipment, removing the need to manage multiple, complex systems and significantly reduces the required floorspace. By employing innovative purification techniques, our solution aims to reduce product losses and improve final drug-product availability.