Ntensify® mini

mRNA production system

For drug discovery & pre-clinical research

The Ntensify® mini is a research-grade RNA production system introducing a novel approach to RNA synthesis and purification. Both synthesis and purification steps are automated in a single system to enable production of up to 48 different RNA constructs at a 2 mg scale (multiplexing) or a single RNA construct at a 100 mg scale (pooled).

The equipment performs the Ntensify® process for cost-effective production of RNA drug substance, with a high-quality profile while minimizing impurities.

Up to
2×24
constructs at 2 mg scale
Up to
100
mg/batch for 1 construct
Only
1
FTE for preparation handling
Only
10
minutes for preparation handling
8 hours
per 24 constructs
Ntensify® mini mixes of reagents with TriLink CleanCap

Mixes of reagents

A single kit containing all the necessary mixes of reagents to synthesize and purify RNA drug substance at reaction volumes from 4 × 0.4 mL to 48 × 0.4 mL.

Supplied ready-to-use with the following certificates:
R&D kit
CoATSE BSESDSAOFRNAse
Average Ntensify® process performance — mRNA (Version 4.5) vs saRNA (Version 6.3)
Scalability

The Ntensify® mini integrates perfectly in our Ntensify® portfolio and provides consistent scalability from medium to large scale production.

Ntensify® product line

Ntensify® product range — mRNA production systems

Ntensify® process performance

Ntensify® process performance - IVT TiterNtensify® process performance - RNA IntegrityNtensify® process performanceNtensify® process performance - Poly(A) tail correct lengthNtensify® process performance - Residual plasmid DNANtensify® process performance - dsRNA content
Flexibility

Key facts
  • Option to select the cap analog or supply your own
  • Option to select your uridine modification
  • Option to use your own nucleotides
  • Reaction scale from 4 × 0.4 mL to 48 × 0.4 mL
  • Compatible with both mRNA and saRNA
Ntensify® mini, mRNA production system for drug discovery and pre-clinical research

With you at every step

We are dedicated to your success with comprehensive training packages to fully educate your team. Our training includes engaging classroom sessions to understand Quantoom Biosciences' cutting-edge manufacturing methods, and also hands-on teaching to ensure your team becomes proficient and autonomous in using our systems. We are here to support you every step of the way.

Quantoom Biosciences Academy
Quantoom Academy hands-on training with the Ntensify® mini

For any questions or requests

Please contact us and we will respond quickly!

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