Ntensify® micro
GMP certified — Good Manufacturing Practice

Bench scale mRNA production system

The Ntensify® micro is the smallest and most compact equipment tailored for the Ntensify® process. Combined with our mixes of reagents kit, this benchtop equipment can produce and purify from 0.4 mg to 160 mg of high-quality mRNA in 3 hours, in a flexible configuration that takes you from a 96 well plate to a 20 mL bioreactor.

Up to 160 mg
3h
workflow
Based on
Ntensify®
process
1-pot IVT
1-step
purification
Scale-down model
of the Ntensify® midi flex
Flexible configuration
From 96 well plate to 20 mL bioreactor
Ntensify® micro mixes of reagents with TriLink CleanCap

Tailored for our mixes of reagents

The Ntensify® micro is tailored to work with our Ntensify® R&D lot, containing all necessary mixes of reagents.

Supplied ready-to-use with the following certificates:

5 quality certificates included

CoATSE BSESDSAOFRNAse

The Ntensify® micro comes pre-loaded with the Ntensify® process, a redesigned and optimized process based on a 1-pot IVT with 1-step purification. This process can be executed in 3 hours and delivers a high-quality RNA with low residual impurities.

Average Ntensify® process performance — mRNA (Version 4.5) vs saRNA (Version 6.3)
Scalability

The Ntensify® micro integrates perfectly in our Ntensify® portfolio and provides consistent scalability from small to large scale production.

Ntensify® product line

Ntensify® product range — mRNA production systems

Ntensify® process performance

Ntensify® process performance - IVT TiterNtensify® process performance - RNA IntegrityNtensify® process performanceNtensify® process performance - Poly(A) tail correct lengthNtensify® process performance - Residual plasmid DNANtensify® process performance - dsRNA content
Ntensify® reaction scales — mano, micro and midi flex
Flexibility

The Ntensify® micro provides throughput flexibility by offering 96 well plate compatibility, including deep-well plates. It can also operate the Ntensify® midi flex 20 mL IVT cavities, enabling scale-down in identical process conditions as the Ntensify® midi flex, our GMP-compliant equipment. This compatibility makes the Ntensify® micro the perfect springboard for future clinical and commercial production.

Key facts
  • Option to select the cap analog or supply your own
  • Option to select your uridine modification
  • Option to use your own nucleotides
  • Reaction scale from 1 to 96 parallel μL-scale reactions, and 20 mL IVT cavities
  • Compatible with both mRNA and saRNA
96 well plate format
Ntensify® micro 96 well plate format
20 mL IVT format
Ntensify® micro 20 mL IVT format

With you at every step

We are dedicated to your success with comprehensive training packages to fully educate your team. Our training includes engaging classroom sessions to understand Quantoom Biosciences' cutting-edge manufacturing methods, and also hands-on teaching to ensure your team becomes proficient and autonomous in using our systems. We are here to support you every step of the way.

Quantoom Biosciences Academy
Quantoom Academy hands-on training with Ntensify® micro

For any questions or requests

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