mRNA production that works simply and simply works
The Ntensify™ mano reagent kit is an all-in-one, cost-effective solution for mRNA production that combines convenience, efficiency, and control. It provides optimized components for both IVT and downstream purification, ensuring high-quality results with reduced variability and time.
Up to 1 mg of mRNA
From linear DNA to purified mRNA in under 3 hours
1 pot IVT with co-transcriptional capping
Supplied with regular and modified uridines (Regular uridine, pseudouridine and methylpseudo uridine)
Optimized for research use only
1-step proprietary silica bead-based purification
7 mixes in total (5 IVT + 2 Purification)
DNA template as positive control included
mRNA production that works simply and simply works
The Ntensify™ mano reagent kit is an all-in-one, cost-effective solution for mRNA production that combines convenience, efficiency, and control. It provides optimized components for both IVT and downstream purification, ensuring high-quality results with reduced variability and time.
Up to 1 mg of mRNA
From linear DNA to purified mRNA in under 3 hours
1 pot IVT with co-transcriptional capping
Supplied with regular and modified uridines (Regular uridine, pseudouridine and methylpseudo uridine)
Optimized for research use only
1-step proprietary silica bead-based purification
7 mixes in total (5 IVT + 2 Purification)
DNA template as positive control included
process
The NtensifyTM platform is a novel approach to mRNA production, achieved through advanced Design of Experiments (DoE) and after four years of optimization. It enables high-yield, low-contaminant mRNA to be produced while simultaneously reducing the overall costs.
The process is construct-agnostic and includes an optimized one-pot IVT with co-transcriptional capping and a redesigned single-step purification to minimize mRNA losses and increase available drug-substance mRNA. It can scale seamlessly from mg-scale (R&D level) to kg-scale (commercial production).
Data obtained with Quantoom’s Ntensify™ process* tested on numerous mRNA constructs
- Number of reactions: > 300
- Number of constructs: 40+
- Construct size ranging from 998 to 10865 nucleotides (mRNA from 998 to 4284 nucleotides / saRNA up to 10865 nucleotides)
* process co-developed with our partner 
process
The NtensifyTM platform is a novel approach to mRNA production, achieved through advanced Design of Experiments (DoE) and after four years of optimization. It enables high-yield, low-contaminant mRNA to be produced while simultaneously reducing the overall costs.
The process is construct-agnostic and includes an optimized one-pot IVT with co-transcriptional capping and a redesigned single-step purification to minimize mRNA losses and increase available drug-substance mRNA. It can scale seamlessly from mg-scale (R&D level) to kg-scale (commercial production).
Data obtained with Quantoom’s Ntensify™ process* tested on numerous mRNA constructs
- Number of reactions: > 300
- Number of constructs: 40+
- Construct size ranging from 998 to 10865 nucleotides (mRNA from 998 to 4284 nucleotides / saRNA up to 10865 nucleotides)
* process co-developed with our partner
product line
product line
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