Our GMP-grade RNA Production System & Disposables

RNA Production

We designed our RNA Production System with end users’ needs in mind, creating a radically different manufacturing technology with two features at its core.

GMP-grade RNA Production System & Disposables
Fridge storing the reagentsIn-Vitro transcription reactionPurification stepsH-vac systemStorage fridge for harvested RNA product

Fridge storing the reagents

In-Vitro transcription reaction

Purification steps

H-vac system

Storage fridge for harvested RNA product

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Intensification & chaining

We can manufacture mRNA at a wide range of capacities thanks to our
sequential-continuous production mode at milliliter-scale. This includes
IVT and mRNA purification, to deliver purified naked RNA.

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Tunable generic process

We have redesigned the production process and validated it for mRNA
and saRNA. The process is adaptable and able to take sequence
specificities into consideration.

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Set of benefits

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    No scale-up needed (pre-) clinical development is already at the final scale, which accelerates your process & product development

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    Single small footprint system that integrates all process steps - no need to invest in a suite of equipment

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    Generic process that is adaptable to your specific RNA construct both for transcription and purification, with polishing options

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    Reduced CoGs thanks to minimal labor & RNA expertise required

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    In vivo validated with multiple RNA constructs to de-risk your product development

Key Numbers

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    Up to 15 g per day over 300 days

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    Up to 75 million doses per year (50 μg)

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